{"id":39,"date":"2025-06-26T15:47:39","date_gmt":"2025-06-26T15:47:39","guid":{"rendered":"https:\/\/june.creatis.insa-lyon.fr\/wordpress\/?page_id=39"},"modified":"2026-02-27T08:13:30","modified_gmt":"2026-02-27T08:13:30","slug":"home","status":"publish","type":"page","link":"https:\/\/june.creatis.insa-lyon.fr\/wordpress\/","title":{"rendered":"Home"},"content":{"rendered":"\n

Modeling nasal airflows for better pathophysiological understanding<\/strong><\/h1>\n\n\n\n

The JUNE project aims to demonstrate that modeling nasal airflows (CFDS) improves the understanding and diagnosis of functional respiratory disorders. It combines medical imaging, artificial intelligence, numerical modeling, and clinical validation to build a reliable digital twin of the nasal cavity. This project will establish quantitative measures of nasal obstruction correlated with clinical criteria.<\/p>\n\n\n\n

Consortium<\/strong><\/h1>\n\n\n\n
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Project details<\/strong><\/h1>\n\n\n\n

Chronic Nasal Obstruction (CNO) concerns 20 to 25% of the general population due to several etiologies (septal deviation, obstructive sleep disorders, chronic rhinosinusitis, post-therapeutic cancer quality of life\u2026). It disrupts sleep and deteriorates all the compartments of the quality of life sometimes to depression. To date, nobody knows the exact component of nasal obstruction which is probably the amalgamation of different mucosal informations (thermo-, presso-, chemoreceptors and free end of the fifth nerve) and all measurement attempts have failed by lack of reliability and reproducibility. This major shortcoming of nasal obstruction leads to diagnosis uncertainties, quantification of symptoms and therapeutic. The place of such complementary exam able to do an objective measure of nasal obstruction is expected by the profession. We can do simple analogies: imagine treated anemia without hemoglobin, deafness without audiogram, heart rhythm disorder without electrocardiogram.<\/p>\n\n\n\n

Methodology<\/strong><\/h1>\n\n\n\n

The project is structured around three main objectives:<\/p>\n\n\n\n